All research outputs are labelled by stage: Registered · Recruiting · In Preparation · Deposited · Documented. No premature clinical claims are made, and no effect estimates are reported ahead of completion and peer review. Statistical analysis plans are pre-specified before data collection. Datasets are archived openly for independent verification. The program is organised into 8 research streams spanning core biomechanics, AI integration, and nutritional science, anchored by 3 registered clinical investigations with a combined planned enrolment of approximately 432 participants.
| Stream ID | Domain | Keywords | PI / Lead | Status |
|---|---|---|---|---|
| RS-001 |
Spine & Load-Tolerance Science
Torque-demand vs. extensor-capacity modelling; spinal segment mechanics under load
|
IAP · L5/S1 Shear · Torque · EMG Trunk · Panjabi |
Dr. Neeraj Mehta |
Active |
| RS-002 |
Gait, Locomotion & Load Distribution
GRF dynamics, COM regulation, plantar load, temporal-spatial gait parameters
|
GRF · Plantar Load · IMU · Symmetry · COM |
Dr. Neeraj Mehta |
Active |
| RS-003 |
Strength & Performance Biomechanics
Force-vector optimisation, SSC mechanics, RFD, kinetic chain load-sharing strategies
|
Force Vectors · RFD · Bar Path · SSC · Fatigue |
Dr. Neeraj Mehta |
Active |
| RS-004 |
Neuromechanical Control
Anti-rotation, anti-lateral flexion, proprioceptive regulation, dynamic mechanical load
|
Proprioception · Co-contraction · HRV · EMG |
Dr. Neeraj Mehta |
Active |
| RS-005 |
Clinical Movement Dysfunction & Rehabilitation
MMSx-SCAN™ multi-site registry; staged correction pathways; load-tolerance restoration
|
MMSx-SCAN · MOVE · BPIT · Kinetic Chain · Rehab |
Dr. Neeraj Mehta |
Recruiting |
| RS-006 |
Prosthetics, Orthotics & Footwear Biomechanics
Human-device interface pressures, compensatory gait, footwear-mediated load redistribution
|
Pressure Map · Device Interface · Footwear · AFO |
Dr. Neeraj Mehta |
Developing |
| RS-007 |
Artificial Intelligence & Biomechanics
AI-driven movement pattern recognition, pose estimation, automated kinematic analysis, predictive load modelling
|
Pose Estimation · ML · Computer Vision · LSTM · Digital Twin |
Dr. Neeraj Mehta |
Active |
| RS-008 |
Nutrition & Biomechanics
Nutritional modulation of musculoskeletal load tolerance, connective tissue integrity, and neuromuscular recovery under mechanical stress
|
Collagen · Protein Synthesis · HRV · Inflammation · Recovery |
Dr. Neeraj Mehta |
Developing |
The central clinical stream of the MMSx Authority research program. Investigates movement dysfunction patterns, staged corrective sequencing, and return-to-activity frameworks using a structured multi-site registry approach. The MMSx-SCAN™ assessment tool provides the inter-rater reliability and normative reference infrastructure for this stream; reliability and normative analyses are in progress and will be reported on completion.
Spinal biomechanics treated as a load-pathway decision problem. Quantifies extensor torque demand vs. muscle capacity under progressive loading — with application to manual handling, rehabilitation, and performance programming.
Mechanical efficiency of high-load and high-velocity movement. Applies force-vector analysis to resistance training, plyometrics, and sport-specific skill — with emphasis on load distribution across kinetic chain segments.
Regulation of joint stability and load tolerance through proprioceptive and neuromuscular mechanisms. Investigates HRV as a systemic marker of mechanical recovery and adaptation under progressive training load.
Integration of machine learning, computer vision, and pose-estimation technologies with clinical biomechanics frameworks. Develops AI-assisted movement screening tools, predictive load models, and automated kinematic assessment pipelines for use across clinical and field-based settings — including the TrainersEye platform.
Investigates the role of nutritional status in modulating musculoskeletal load tolerance, connective tissue integrity, and neuromuscular recovery under progressive mechanical stress. Bridges nutritional biochemistry with applied biomechanics to understand how macro- and micronutrient availability influences tissue-level load capacity and mechanical adaptation.
All interventional research is pre-registered on ClinicalTrials.gov prior to data collection. Study IDs are permanent internal identifiers cross-referenced against NCT numbers, Zenodo/OSF archives, and DOI-registered outputs. The table below lists the 3 registered clinical investigations together with the MMSx-SCAN™ reliability dataset and the multi-site registry currently in development. Combined planned enrolment across the registered trials: approximately 432 participants. No effect estimates are reported until each study completes and is peer-reviewed.
| Study ID | Study Title & Design | Planned n | Status | NCT / Registry | DOI / Archive | Sites |
|---|---|---|---|---|---|---|
| MMSx-STU-001 |
MOVE Protocol — Movement-Oriented Velocity of Engagement
Multi-site interventional case-series · 8-week · 4-phase rehabilitation framework · GCP ICH E6(R3)
|
40 Planned | Registered · Results pending | NCT07220200 |
JMMBS (in prep)
|
GFFI New Delhi BodyGNTX USA IIKBS |
| MMSx-STU-002 |
BPIT 5-Line Pilot — Strength, HRV & Injury-Risk Outcomes
Prospective single-site interventional · Paired t-tests α=0.05 · Cohen's d · Pre-registered SAP
|
23 Planned | Registered · Results pending | NCT07296640 |
10.5281/zenodo.17594977
method archive
|
BodyGNTX USA |
| MMSx-STU-003 |
BPIT Multi-Site Study — Strength, HRV & Reproducibility
Multi-site single-arm interventional · Mixed-effects ANOVA · Cross-site reproducibility
|
369 Planned | Registered · Recruiting | NCT07256717 |
archive on completion
|
BodyGNTX · GFFI IIKBS · AIHFT BFS |
| MMSx-DAT-004 |
MMSx-SCAN™ Movement Assessment Dataset
Open dataset deposit · inter-rater reliability & normative analysis in progress (ICC, SEM, MDC95)
|
Deposited OSF | Dataset deposited · Analysis ongoing | — |
10.17605/OSF.IO/F87N2 | Multi-site · multiple raters |
| MMSx-STU-005 |
MMSx-SCAN™ Multi-Site Movement Registry
Observational registry · cross-sectional · optional 4-week and 12-week follow-up
|
In dev. Not yet registered | In development | NCT pending |
— |
International |
Primary datasets and framework documentation are archived under CC BY 4.0 with permanent DOIs. Anonymised participant data, codebooks, and analysis scripts are made available for independent verification as each study completes. Planned enrolment across the registered clinical trials is approximately 432 participants. In addition, MMSx Authority has produced 100+ monographs and educational titles and 40+ exercise blueprints archived through IMSO, Zenodo, and the JMMBS publishing infrastructure.
Proprietary biomechanical frameworks developed within the MMSx Authority research program — spanning core movement mechanics, load modelling, clinical assessment, AI integration, and nutritional biomechanics. DOI-registered frameworks are archived on Zenodo or OSF; others are documented and serve as the operational models for registered investigations and educational outputs. Where a framework is evaluated in a registered trial, outcomes are reported only on completion. Major frameworks are listed below.
The standards below are adopted for the design, conduct, and reporting of MMSx Authority research. "Adopted" indicates the standard governs the relevant work; reporting-stage standards (e.g. CONSORT, PRISMA) apply as the corresponding studies and reviews reach completion.
| Standard / Framework | Domain | Applies To | Status |
|---|---|---|---|
| GCP ICH E6(R3) | Good Clinical Practice — trial conduct, documentation, investigator responsibilities | NCT07220200 · NCT07296640 · NCT07256717 | Adopted |
| Declaration of Helsinki | Ethical principles for medical research involving human subjects (2013 revision) | All clinical investigations | Adopted |
| CONSORT 2010 | Consolidated Standards of Reporting Trials — interventional study reporting | Interventional trials, at reporting | On completion |
| STROBE | Strengthening the Reporting of Observational Studies in Epidemiology | Observational registry & dataset | On completion |
| PRISMA 2020 | Preferred Reporting Items for Systematic Reviews and Meta-Analyses | Systematic reviews (in preparation) | On completion |
| Pre-Registered SAP | Statistical Analysis Plan locked before data collection | All interventional studies | Adopted |
| Open Data Policy | CC BY 4.0 datasets archived on OSF and Zenodo — independently downloadable and verifiable | Deposited datasets & frameworks | Adopted |
| COI Disclosure | Conflict of interest disclosed on outputs; multi-site data collected by independently employed assessors | All outputs | Adopted |
| IMSO S101 | Movement-intelligence assessment standard — MMSx Authority proprietary governance framework | MMSx-SCAN™ assessment | Adopted |
The institute, journal, and principal investigator carry permanent machine-readable identifiers enabling unambiguous citation and cross-database disambiguation by scholarly indexing systems.